This prophecy talks about a time when men and women's rejection of God will be so strong that He will in turn send a strong delusion on them that they will believe THE lie. Not one particular, but rather the greatest lie of all lies. There's been some debate on what that is, but the general consensus is that this delusion will cause people to reject all or most truth and openly and willfully accept any and all lies presented to them.
(*Do you have a better description, or did you find an error? Please let me know.